DKC1 antibody (N-Term)

Catalog No. ABIN2778770

This anti-DKC1 antibody is a Rabbit Polyclonal antibody detecting DKC1 in WB. Suitable for Human, Mouse, Rat, Rabbit, Cow, Dog, Sheep, Zebrafish (Danio rerio), Guinea Pig, Horse, Goat and Saccharomyces cerevisiae.

Quick Overview for DKC1 antibody (N-Term) (ABIN2778770)

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Sheep, Zebrafish (Danio rerio), Guinea Pig, Horse, Goat, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DKC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DKC1 Antibody

Binding Specificity: N-Term

Sequence: EFLIKPESKV AKLDTSQWPL LLKNFDKLNV RTTHYTPLAC GSNPLKREIG

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 86%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DKC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DKC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 514 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DKC1

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Alternative Name: DKC1

Background: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also incl
Alias Symbols: DKC, NAP57, NOLA4, XAP101, dyskerin, CBF5, DKCX
Protein Interaction Partner: UBC, LIN28A, WWOX, ERG, SUZ12, EED, RNF2, BMI1, HDAC11, DKC1, RUVBL2, RUVBL1, TERT, CSNK2A1, PAXIP1, ESR1, RPLP0P6, LSM2, DDX24, NHP2, RBM28, GAR1, NOP58, PTGES3, POLR1C, SRP14, RPSA, CAND1, NOP10, FBL, NAF1, YWHAZ, ARRB2, ARRB1, SHQ1, TERC, MAPK6, Ybx1,
Protein Size: 514

Molecular Weight: 58 kDa

Gene ID: 1736

NCBI Accession: NM_001363, NP_001354

UniProt: O60832

Pathways: Telomere Maintenance